Successful treatment with apatinib for refractory recurrent malignant gliomas: a case series
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چکیده
منابع مشابه
Successful treatment with apatinib for refractory recurrent malignant gliomas: a case series
Malignant glioma (MG) is a common and refractory primary tumor with a high recurrence rate. There is still a lack of effective therapy for recurrent MG (rMG). We present here two cases of refractory rMG treated using apatinib, which is a new highly selective inhibitor to VEGFR. Case 1, a 37-year-old female, was diagnosed with recurrent intracerebral high-grade glioma and failed to almost all tr...
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RATIONALE The standard treatment for ovarian cancer is chemotherapy with 2 drugs (taxanes and platinum drugs). However, the traditional combination of the 2 drugs has many adverse effects (AEs) and the cancer cells will quickly become resistant to the drugs. Apatinib is a small-molecule antiangiogenic agent which has shown promising therapeutic effects against diverse tumor types, but it still ...
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ژورنال
عنوان ژورنال: OncoTargets and Therapy
سال: 2017
ISSN: 1178-6930
DOI: 10.2147/ott.s119129